Cyclophilin D Promotes Acute, but Not Chronic, Kidney Injury in a Mouse Model of Aristolochic Acid Toxicity

The plant-derived toxin, aristolochic acid (AA), is the cause of Chinese Herb Nephropathy and Balkan Nephropathy. Ingestion of high dose AA induces acute kidney injury, while chronic low dose ingestion leads to progressive kidney disease. Ingested AA is taken up by tubular epithelial cells of the ki...

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Detalles Bibliográficos
Autores principales: Leong, Khai Gene, Ozols, Elyce, Kanellis, John, Ma, Frank Y., Nikolic-Paterson, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8539043/
https://www.ncbi.nlm.nih.gov/pubmed/34678993
http://dx.doi.org/10.3390/toxins13100700

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8539043/
https://www.ncbi.nlm.nih.gov/pubmed/34678993
http://dx.doi.org/10.3390/toxins13100700

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