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Critical Drug Loss Induced by Silicone and Polyurethane Implantable Catheters in a Simulated Infusion Setup with Three Model Drugs

Silicone and polyurethane are biocompatible materials used for the manufacture of implantable catheters, but are known to induce drug loss by sorption, causing potentially important clinical consequences. Despite this, their impact on the drugs infused through them is rarely studied, or they are stu...

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Detalles Bibliográficos
Autores principales: Tokhadzé, Nicolas, Chennell, Philip, Pereira, Bruno, Mailhot-Jensen, Bénédicte, Sautou, Valérie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8539077/
https://www.ncbi.nlm.nih.gov/pubmed/34684002
http://dx.doi.org/10.3390/pharmaceutics13101709