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The Contribution of Complement to the Pathogenesis of IgA Nephropathy: Are Complement-Targeted Therapies Moving from Rare Disorders to More Common Diseases?

Primary IgA nephropathy (IgAN) is a leading cause of chronic kidney disease and kidney failure for which there is no disease-specific treatment. However, this could change, since novel therapeutic approaches are currently being assessed in clinical trials, including complement-targeting therapies. A...

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Detalles Bibliográficos
Autores principales: Poppelaars, Felix, Faria, Bernardo, Schwaeble, Wilhelm, Daha, Mohamed R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8539100/
https://www.ncbi.nlm.nih.gov/pubmed/34682837
http://dx.doi.org/10.3390/jcm10204715