OSMI-1 Enhances TRAIL-Induced Apoptosis through ER Stress and NF-κB Signaling in Colon Cancer Cells

Levels of O-GlcNAc transferase (OGT) and hyper-O-GlcNAcylation expression levels are associated with cancer pathogenesis. This study aimed to find conditions that maximize the therapeutic effect of cancer and minimize tissue damage by combining an OGT inhibitor (OSMI-1) and tumor necrosis factor-rel...

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Detalles Bibliográficos
Autores principales: Lee, Su-Jin, Lee, Da-Eun, Choi, Soo-Young, Kwon, Oh-Shin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8539180/
https://www.ncbi.nlm.nih.gov/pubmed/34681736
http://dx.doi.org/10.3390/ijms222011073

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8539180/
https://www.ncbi.nlm.nih.gov/pubmed/34681736
http://dx.doi.org/10.3390/ijms222011073

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