Cytosolic Phospholipase A2 Is Required for Fexofenadine’s Therapeutic Effects against Inflammatory Bowel Disease in Mice

Inflammatory Bowel Disease (IBD) is an autoimmune condition with complicated pathology and diverse clinical signs. TNFα is believed to play a crucial role in the pathogenesis of IBD. We recently identified fexofenadine, a well-known antagonist of histamine H1 receptor, as a novel inhibitor of TNFα s...

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Detalles Bibliográficos
Autores principales: Zhao, Xiangli, Liu, Ronghan, Chen, Yuehong, Hettinghouse, Aubryanna, Liu, Chuanju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8539349/
https://www.ncbi.nlm.nih.gov/pubmed/34681815
http://dx.doi.org/10.3390/ijms222011155

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8539349/
https://www.ncbi.nlm.nih.gov/pubmed/34681815
http://dx.doi.org/10.3390/ijms222011155

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