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Cytosolic Phospholipase A2 Is Required for Fexofenadine’s Therapeutic Effects against Inflammatory Bowel Disease in Mice
Inflammatory Bowel Disease (IBD) is an autoimmune condition with complicated pathology and diverse clinical signs. TNFα is believed to play a crucial role in the pathogenesis of IBD. We recently identified fexofenadine, a well-known antagonist of histamine H1 receptor, as a novel inhibitor of TNFα s...
Autores principales: | Zhao, Xiangli, Liu, Ronghan, Chen, Yuehong, Hettinghouse, Aubryanna, Liu, Chuanju |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8539349/ https://www.ncbi.nlm.nih.gov/pubmed/34681815 http://dx.doi.org/10.3390/ijms222011155 |
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