Direct and Base Excision Repair-Mediated Regulation of a GC-Rich cis-Element in Response to 5-Formylcytosine and 5-Carboxycytosine

Stepwise oxidation of the epigenetic mark 5-methylcytosine and base excision repair (BER) of the resulting 5-formylcytosine (5-fC) and 5-carboxycytosine (5-caC) may provide a mechanism for reactivation of epigenetically silenced genes; however, the functions of 5-fC and 5-caC at defined gene element...

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Detalles Bibliográficos
Autores principales: Müller, Nadine, Ponkkonen, Eveliina, Carell, Thomas, Khobta, Andriy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8539351/
https://www.ncbi.nlm.nih.gov/pubmed/34681690
http://dx.doi.org/10.3390/ijms222011025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8539351/
https://www.ncbi.nlm.nih.gov/pubmed/34681690
http://dx.doi.org/10.3390/ijms222011025

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