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Type 1 Diabetes Mellitus and the First Trimester Placenta: Hyperglycemia-Induced Effects on Trophoblast Proliferation, Cell Cycle Regulators, and Invasion

Type 1 diabetes mellitus (T1DM) is associated with reduced fetal growth in early pregnancy, but a contributing role of the placenta has remained elusive. Thus, we investigated whether T1DM alters placental development in the first trimester. Using a protein array, the level of 60 cell-cycle-related...

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Detalles Bibliográficos
Autores principales: Majali-Martinez, Alejandro, Weiss-Fuchs, Ursula, Miedl, Heidi, Forstner, Desiree, Bandres-Meriz, Julia, Hoch, Denise, Djelmis, Josip, Ivanisevic, Marina, Hiden, Ursula, Gauster, Martin, Desoye, Gernot
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8539403/
https://www.ncbi.nlm.nih.gov/pubmed/34681648
http://dx.doi.org/10.3390/ijms222010989