Inflammation Induces Changes in the Functional Expression of P-gp, BCRP, and MRP2: An Overview of Different Models and Consequences for Drug Disposition

The ATP-binding cassette (ABC) transporters play a key role in drug pharmacokinetics. These membrane transporters expressed within physiological barriers can be a source of pharmacokinetic variability. Changes in ABC transporter expression and functionality may consequently affect the disposition of...

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Detalles Bibliográficos
Autores principales: Saib, Sonia, Delavenne, Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8539483/
https://www.ncbi.nlm.nih.gov/pubmed/34683838
http://dx.doi.org/10.3390/pharmaceutics13101544

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8539483/
https://www.ncbi.nlm.nih.gov/pubmed/34683838
http://dx.doi.org/10.3390/pharmaceutics13101544

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