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Vaccinia Virus Expressing Interferon Regulatory Factor 3 Induces Higher Protective Immune Responses against Lethal Poxvirus Challenge in Atopic Organism

Vaccinia virus (VACV) is an enveloped DNA virus from the Orthopoxvirus family, various strains of which were used in the successful eradication campaign against smallpox. Both original and newer VACV-based replicating vaccines reveal a risk of serious complications in atopic individuals. VACV encode...

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Detalles Bibliográficos
Autores principales: Pilna, Hana, Hajkova, Vera, Knitlova, Jarmila, Liskova, Jana, Elsterova, Jana, Melkova, Zora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8539567/
https://www.ncbi.nlm.nih.gov/pubmed/34696416
http://dx.doi.org/10.3390/v13101986