Direct Conversion of 3-(2-Nitroethyl)-1H-Indoles into 2-(1H-Indol-2-yl)Acetonitriles

The recently discovered [4+1]-spirocyclization of nitroalkenes to indoles provided a convenient new approach to 2-(1H-indol-2-yl)acetonitriles. However, this reaction was complicated by the formation of inert 3-(2-nitroethyl)-1H-indole byproducts. Herein, we offer a workaround this problem that allo...

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Detalles Bibliográficos
Autores principales: Aksenov, Alexander V., Aksenov, Nicolai A., Aleksandrova, Elena V., Aksenov, Dmitrii A., Grishin, Igor Yu., Sorokina, Elena A., Wenger, Allison, Rubin, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8539596/
https://www.ncbi.nlm.nih.gov/pubmed/34684712
http://dx.doi.org/10.3390/molecules26206132

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8539596/
https://www.ncbi.nlm.nih.gov/pubmed/34684712
http://dx.doi.org/10.3390/molecules26206132

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