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Costunolide Loaded in pH-Responsive Mesoporous Silica Nanoparticles for Increased Stability and an Enhanced Anti-Fibrotic Effect

Liver fibrosis remains a significant public health problem. However, few drugs have yet been validated. Costunolide (COS), as a monomeric component of the traditional Chinese medicinal herb Saussurea Lappa, has shown excellent anti-fibrotic efficacy. However, COS displays very poor aqueous solubilit...

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Detalles Bibliográficos
Autores principales: Niu, Xia, Wang, Xiaomei, Niu, Bingyu, Meng, Yanan, He, Hongwei, Wang, Yucheng, Li, Guiling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8539632/
https://www.ncbi.nlm.nih.gov/pubmed/34681175
http://dx.doi.org/10.3390/ph14100951