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Costunolide Loaded in pH-Responsive Mesoporous Silica Nanoparticles for Increased Stability and an Enhanced Anti-Fibrotic Effect
Liver fibrosis remains a significant public health problem. However, few drugs have yet been validated. Costunolide (COS), as a monomeric component of the traditional Chinese medicinal herb Saussurea Lappa, has shown excellent anti-fibrotic efficacy. However, COS displays very poor aqueous solubilit...
Autores principales: | Niu, Xia, Wang, Xiaomei, Niu, Bingyu, Meng, Yanan, He, Hongwei, Wang, Yucheng, Li, Guiling |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8539632/ https://www.ncbi.nlm.nih.gov/pubmed/34681175 http://dx.doi.org/10.3390/ph14100951 |
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