Xeno-Nucleic Acid (XNA) 2’-Fluoro-Arabino Nucleic Acid (FANA) Aptamers to the Receptor-Binding Domain of SARS-CoV-2 S Protein Block ACE2 Binding

The causative agent of COVID-19, SARS-CoV-2, gains access to cells through interactions of the receptor-binding domain (RBD) on the viral S protein with angiotensin-converting enzyme 2 (ACE2) on the surface of human host cells. Systematic evolution of ligands by exponential enrichment (SELEX) was us...

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Detalles Bibliográficos
Autores principales: Alves Ferreira-Bravo, Irani, DeStefano, Jeffrey J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8539646/
https://www.ncbi.nlm.nih.gov/pubmed/34696413
http://dx.doi.org/10.3390/v13101983

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8539646/
https://www.ncbi.nlm.nih.gov/pubmed/34696413
http://dx.doi.org/10.3390/v13101983

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