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DAKS1, a Kunitz Scaffold Peptide from the Venom Gland of Deinagkistrodon acutus Prevents Carotid-Artery and Middle-Cerebral-Artery Thrombosis via Targeting Factor XIa

Scaffold-based peptides (SBPs) are fragments of large proteins that are characterized by potent bioactivity, high thermostability, and low immunogenicity. Some SBPs have been approved by the FDA for human use. In the present study, we developed SBPs from the venom gland of Deinagkistrodon acutus (D....

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Detalles Bibliográficos
Autores principales: Jia, Zhiping, Liu, Yunyang, Ji, Xiaoru, Zheng, Yizheng, Li, Zhengyang, Jiang, Shuai, Li, Hongjin, Kong, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8539665/
https://www.ncbi.nlm.nih.gov/pubmed/34681191
http://dx.doi.org/10.3390/ph14100966