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DAKS1, a Kunitz Scaffold Peptide from the Venom Gland of Deinagkistrodon acutus Prevents Carotid-Artery and Middle-Cerebral-Artery Thrombosis via Targeting Factor XIa
Scaffold-based peptides (SBPs) are fragments of large proteins that are characterized by potent bioactivity, high thermostability, and low immunogenicity. Some SBPs have been approved by the FDA for human use. In the present study, we developed SBPs from the venom gland of Deinagkistrodon acutus (D....
Autores principales: | Jia, Zhiping, Liu, Yunyang, Ji, Xiaoru, Zheng, Yizheng, Li, Zhengyang, Jiang, Shuai, Li, Hongjin, Kong, Yi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8539665/ https://www.ncbi.nlm.nih.gov/pubmed/34681191 http://dx.doi.org/10.3390/ph14100966 |
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