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Chitosan Oleate Coated PLGA Nanoparticles as siRNA Drug Delivery System

Oligonucleotide therapeutics such as miRNAs and siRNAs represent a class of molecules developed to modulate gene expression by interfering with ribonucleic acids (RNAs) and protein synthesis. These molecules are characterized by strong instability and easy degradation due to nuclease enzymes. To avo...

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Detalles Bibliográficos
Autores principales: Miele, Dalila, Xia, Xin, Catenacci, Laura, Sorrenti, Milena, Rossi, Silvia, Sandri, Giuseppina, Ferrari, Franca, Rossi, John J., Bonferoni, Maria Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8539707/
https://www.ncbi.nlm.nih.gov/pubmed/34684009
http://dx.doi.org/10.3390/pharmaceutics13101716