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Copper-Containing Nanoparticles and Organic Complexes: Metal Reduction Triggers Rapid Cell Death via Oxidative Burst

Copper-containing agents are promising antitumor pharmaceuticals due to the ability of the metal ion to react with biomolecules. In the current study, we demonstrate that inorganic Cu(2+) in the form of oxide nanoparticles (NPs) or salts, as well as Cu ions in the context of organic complexes (oxida...

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Detalles Bibliográficos
Autores principales: Tsymbal, Sergey A., Moiseeva, Anna A., Agadzhanian, Nikol A., Efimova, Svetlana S., Markova, Alina A., Guk, Dmitry A., Krasnovskaya, Olga O., Alpatova, Victoria M., Zaitsev, Andrei V., Shibaeva, Anna V., Tatarskiy, Victor V., Dukhinova, Marina S., Ol’shevskaya, Valentina A., Ostroumova, Olga S., Beloglazkina, Elena K., Shtil, Alexander A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8539714/
https://www.ncbi.nlm.nih.gov/pubmed/34681725
http://dx.doi.org/10.3390/ijms222011065