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ELTD1 Activation Induces an Endothelial-EMT Transition to a Myofibroblast Phenotype

ELTD1 is expressed in endothelial and vascular smooth muscle cells and has a role in angiogenesis. It has been classified as an adhesion GPCR, but as yet, no ligand has been identified and its function remains unknown. To establish its role, ELTD1 was overexpressed in endothelial cells. Expression a...

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Detalles Bibliográficos
Autores principales: Sheldon, Helen, Alexander, John, Bridges, Esther, Moreira, Lucia, Reilly, Svetlana, Ang, Koon Hwee, Wang, Dian, Lin, Salwa, Haider, Syed, Banham, Alison H., Harris, Adrian L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8539764/
https://www.ncbi.nlm.nih.gov/pubmed/34681953
http://dx.doi.org/10.3390/ijms222011293