In Vitro Anti-Tubulin Activity on MCF10A Cell Line and In Silico Rigid/Semiflexible-Residues Docking, of Two Lignans from Bursera Fagaroides var. Fagaroides

Podophyllotoxins are natural lignans with known cytotoxic activity on several cell lines. The structural basis for their actions is mainly by the aryltetralin-lignan skeleton. Authors have proposed a cytotoxic mechanism of podophyllotoxins through the topoisomerase-II inhibition activity; however, s...

Descripción completa

Detalles Bibliográficos
Autores principales: Rodríguez-López, Verónica, Millán-Pacheco, César, González-Christen, Judith, Anaya-Ruíz, Maricruz, Peña-Morán, Omar Aristeo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8539788/
https://www.ncbi.nlm.nih.gov/pubmed/34684736
http://dx.doi.org/10.3390/molecules26206155

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8539788/
https://www.ncbi.nlm.nih.gov/pubmed/34684736
http://dx.doi.org/10.3390/molecules26206155

Ejemplares similares