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CCR5+ T-Cells Homed to the Liver Exhibit Inflammatory and Profibrogenic Signatures in Chronic HIV/HCV-Coinfected Patients

Liver fibrosis is accelerated in patients coinfected with hepatitis C virus and human immunodeficiency virus (HIV), compared with HCV monoinfected patients, although the underlying mechanisms are unknown. We hypothesize that T cells expressing the HIV co-receptor, chemokine receptor 5 (CCR5), prefer...

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Detalles Bibliográficos
Autores principales: Shrivastava, Shikha, Kottilil, Shyam, Sherman, Kenneth E., Masur, Henry, Tang, Lydia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8539814/
https://www.ncbi.nlm.nih.gov/pubmed/34696504
http://dx.doi.org/10.3390/v13102074