Cargando…
CCR5+ T-Cells Homed to the Liver Exhibit Inflammatory and Profibrogenic Signatures in Chronic HIV/HCV-Coinfected Patients
Liver fibrosis is accelerated in patients coinfected with hepatitis C virus and human immunodeficiency virus (HIV), compared with HCV monoinfected patients, although the underlying mechanisms are unknown. We hypothesize that T cells expressing the HIV co-receptor, chemokine receptor 5 (CCR5), prefer...
Autores principales: | Shrivastava, Shikha, Kottilil, Shyam, Sherman, Kenneth E., Masur, Henry, Tang, Lydia |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8539814/ https://www.ncbi.nlm.nih.gov/pubmed/34696504 http://dx.doi.org/10.3390/v13102074 |
Ejemplares similares
-
Multitarget Direct‐Acting Antiviral Therapy Is Associated With Superior Immunologic Recovery in Patients Coinfected With Human Immunodeficiency Virus and Hepatitis C Virus
por: Shrivastava, Shikha, et al.
Publicado: (2018) -
CCR5 receptor antagonism inhibits hepatitis C virus (HCV) replication in vitro
por: Blackard, Jason T., et al.
Publicado: (2019) -
Peripheral blood correlates of virologic relapse after Sofosbuvir and Ribavirin treatment of Genotype-1 HCV infection
por: Orr, Cody, et al.
Publicado: (2020) -
Dynamic Changes of Post-Translationally Modified Forms of CXCL10 and Soluble DPP4 in HCV Subjects Receiving Interferon-Free Therapy
por: Meissner, Eric G., et al.
Publicado: (2015) -
Hepatitis C Virus Relapse After Ultrashort Direct-Acting Antiviral Therapy Associates With Expression of Genes Involved With Natural Killer-Cell and CD8(+) T-Cell Function
por: Orr, Cody, et al.
Publicado: (2021)