HSV-1 ICP22 Is a Selective Viral Repressor of Cellular RNA Polymerase II-Mediated Transcription Elongation

The Herpes Simplex Virus (HSV-1) immediate-early protein ICP22 interacts with cellular proteins to inhibit host cell gene expression and promote viral gene expression. ICP22 inhibits phosphorylation of Ser2 of the RNA polymerase II (pol II) carboxyl-terminal domain (CTD) and productive elongation of...

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Detalles Bibliográficos
Autores principales: Isa, Nur Firdaus, Bensaude, Olivier, Aziz, Nadiah C., Murphy, Shona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8539892/
https://www.ncbi.nlm.nih.gov/pubmed/34696162
http://dx.doi.org/10.3390/vaccines9101054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8539892/
https://www.ncbi.nlm.nih.gov/pubmed/34696162
http://dx.doi.org/10.3390/vaccines9101054

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