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Protease-Triggered Release of Stabilized CXCL12 from Coated Scaffolds in an Ex Vivo Wound Model

Biomaterials are designed to improve impaired healing of injured tissue. To accomplish better cell integration, we suggest to coat biomaterial surfaces with bio-functional proteins. Here, a mussel-derived surface-binding peptide is used and coupled to CXCL12 (stromal cell-derived factor 1α), a chemo...

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Detalles Bibliográficos
Autores principales: Spiller, Sabrina, Wippold, Tom, Bellmann-Sickert, Kathrin, Franz, Sandra, Saalbach, Anja, Anderegg, Ulf, Beck-Sickinger, Annette G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8539926/
https://www.ncbi.nlm.nih.gov/pubmed/34683890
http://dx.doi.org/10.3390/pharmaceutics13101597