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Albumin-EDTA-Vanadium Is a Powerful Anti-Proliferative Agent, Following Entrance into Glioma Cells via Caveolae-Mediated Endocytosis

Human serum albumin (HSA) is efficiently taken up by cancer cells as a source of carbon and energy. In this study, we prepared a monomodified derivative of HSA covalently linked to an EDTA derivative and investigated its efficacy to shuttle weakly anti-proliferative EDTA associating ligands such as...

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Detalles Bibliográficos
Autores principales: Cooper, Itzik, Ravid, Orly, Rand, Daniel, Atrakchi, Dana, Shemesh, Chen, Bresler, Yael, Ben-Nissan, Gili, Sharon, Michal, Fridkin, Mati, Shechter, Yoram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8540012/
https://www.ncbi.nlm.nih.gov/pubmed/34683850
http://dx.doi.org/10.3390/pharmaceutics13101557