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Therapeutic Interaction of Apatinib and Chidamide in T-cell Acute Lymphoblastic Leukemia through Interference with Mitochondria Associated Biogenesis and Intrinsic Apoptosis

T-cell acute lymphoblastic leukemia (T-ALL) shows poor clinical outcome and has limited therapeutic options, indicating that new treatment approaches for this disease are urgently required. Our previous study demonstrated that apatinib, an orally selective VEGFR-2 antagonist, is highly effective in...

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Detalles Bibliográficos
Autores principales: Zhong, Mengya, Lin, Fusheng, Jiang, Yuelong, Pan, Guangchao, Tan, Jinshui, Zhou, Hui, Lai, Qian, Chen, Qinwei, Deng, Manman, Zha, Jie, Xu, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8540063/
https://www.ncbi.nlm.nih.gov/pubmed/34683119
http://dx.doi.org/10.3390/jpm11100977