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A Strategy for Selective Deletion of Autoimmunity-Related T Cells by pMHC-Targeted Delivery

Autoimmune diseases such as rheumatoid arthritis are caused by immune system recognition of self-proteins and subsequent production of effector T cells that recognize and attack healthy tissue. Therapies for these diseases typically utilize broad immune suppression, which can be effective, but which...

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Detalles Bibliográficos
Autores principales: Goldberg, Shalom D., Felix, Nathan, McCauley, Michael, Eberwine, Ryan, Casta, Lou, Haskell, Kathleen, Lin, Tricia, Palovick, Elizabeth, Klein, Donna, Getts, Lori, Getts, Robert, Zhou, Mimi, Bansal-Pakala, Pratima, Dudkin, Vadim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8540115/
https://www.ncbi.nlm.nih.gov/pubmed/34683962
http://dx.doi.org/10.3390/pharmaceutics13101669