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TNF-Mediated Inhibition of Classical Swine Fever Virus Replication Is IRF1-, NF-κB- and JAK/STAT Signaling-Dependent

The sera from pigs infected with virulent classical swine fever virus (CSFV) contain substantial amounts of tumor necrosis factor (TNF), a prototype proinflammatory cytokine with pleiotropic activities. TNF limits the replication of CSFV in cell culture. In order to investigate the signaling involve...

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Detalles Bibliográficos
Autores principales: Liniger, Matthias, Gerber, Markus, Renzullo, Sandra, García-Nicolás, Obdulio, Ruggli, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8540133/
https://www.ncbi.nlm.nih.gov/pubmed/34696447
http://dx.doi.org/10.3390/v13102017