Cargando…

TNF-Mediated Inhibition of Classical Swine Fever Virus Replication Is IRF1-, NF-κB- and JAK/STAT Signaling-Dependent

The sera from pigs infected with virulent classical swine fever virus (CSFV) contain substantial amounts of tumor necrosis factor (TNF), a prototype proinflammatory cytokine with pleiotropic activities. TNF limits the replication of CSFV in cell culture. In order to investigate the signaling involve...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liniger, Matthias, Gerber, Markus, Renzullo, Sandra, García-Nicolás, Obdulio, Ruggli, Nicolas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8540133/ https://www.ncbi.nlm.nih.gov/pubmed/34696447 http://dx.doi.org/10.3390/v13102017

Ejemplares similares

Immune Responses Against Classical Swine Fever Virus: Between Ignorance and Lunacy
por: Summerfield, Artur, et al.
Publicado: (2015)

A Polyuridine Insertion in the 3′ Untranslated Region of Classical Swine Fever Virus Activates Immunity and Reduces Viral Virulence in Piglets
por: Wang, Miaomiao, et al.
Publicado: (2020)

Clustering of classical swine fever virus isolates by codon pair bias
por: Leifer, Immanuel, et al.
Publicado: (2011)

Abrogation of the RNase activity of E(rns) in a low virulence classical swine fever virus enhances the humoral immune response and reduces virulence, transmissibility, and persistence in pigs
por: Wang, Miaomiao, et al.
Publicado: (2021)

In-yeast reconstruction of the African swine fever virus genome isolated from clinical samples
por: Labroussaa, Fabien, et al.
Publicado: (2021)

Removal of the E(rns) RNase Activity and of the 3′ Untranslated Region Polyuridine Insertion in a Low-Virulence Classical Swine Fever Virus Triggers a Cytokine Storm and Lethal Disease
por: Wang, Miaomiao, et al.
Publicado: (2022)

N(pro) of classical swine fever virus contributes to pathogenicity in pigs by preventing type I interferon induction at local replication sites
por: Tamura, Tomokazu, et al.
Publicado: (2014)

Cell fate in antiviral response arises in the crosstalk of IRF, NF-κB and JAK/STAT pathways
por: Czerkies, Maciej, et al.
Publicado: (2018)

The Structure of Classical Swine Fever Virus N(pro): A Novel Cysteine Autoprotease and Zinc-Binding Protein Involved in Subversion of Type I Interferon Induction
por: Gottipati, Keerthi, et al.
Publicado: (2013)

Postnatal Persistent Infection with Classical Swine Fever Virus and Its Immunological Implications
por: Muñoz-González, Sara, et al.
Publicado: (2015)

Efficacy of a live attenuated vaccine in classical swine fever virus postnatally persistently infected pigs
por: Muñoz-González, Sara, et al.
Publicado: (2015)

Autophagy enhances the replication of classical swine fever virus in vitro
por: Pei, Jingjing, et al.
Publicado: (2013)

Intracellular expression of IRF9 Stat fusion protein overcomes the defective Jak-Stat signaling and inhibits HCV RNA replication
por: Poat, Bret, et al.
Publicado: (2010)

MDA5 Can Be Exploited as Efficacious Genetic Adjuvant for DNA Vaccination against Lethal H5N1 Influenza Virus Infection in Chickens
por: Liniger, Matthias, et al.
Publicado: (2012)

MG132 Attenuates the Replication of Classical Swine Fever Virus in vitro
por: Chen, Yuming, et al.
Publicado: (2020)

Classical Swine Fever: A Truly Classical Swine Disease
por: Wang, Fun-In, et al.
Publicado: (2020)

Regulatory Networks Involving STATs, IRFs, and NFκB in Inflammation
por: Platanitis, Ekaterini, et al.
Publicado: (2018)

Lactate facilitates classical swine fever virus replication by enhancing cholesterol biosynthesis
por: Zou, Xiaodong, et al.
Publicado: (2022)

Vulnerability of the British swine industry to classical swine fever
por: Porphyre, Thibaud, et al.
Publicado: (2017)

Porcine Viperin protein inhibits the replication of classical swine fever virus (CSFV) in vitro
por: Li, Wenliang, et al.
Publicado: (2017)

Cloning and Identification of PK15 Cells for Enhanced Replication of Classical Swine Fever Virus
por: Yin, Mei, et al.
Publicado: (2020)

PKR activation enhances replication of classical swine fever virus in PK-15 cells
por: Liu, Wen-Jun, et al.
Publicado: (2015)

Classical Swine Fever—An Updated Review
por: Blome, Sandra, et al.
Publicado: (2017)

The baseline immunological and hygienic status of pigs impact disease severity of African swine fever
por: Radulovic, Emilia, et al.
Publicado: (2022)

Npro of Classical Swine Fever Virus Suppresses Type III Interferon Production by Inhibiting IRF1 Expression and Its Nuclear Translocation
por: Cao, Tong, et al.
Publicado: (2019)

Classical swine fever virus triggers RIG-I and MDA5-dependent signaling pathway to IRF-3 and NF-κB activation to promote secretion of interferon and inflammatory cytokines in porcine alveolar macrophages
por: Dong, Xiao-Ying, et al.
Publicado: (2013)

Classical swine fever virus replicated poorly in cells from MxA transgenic pigs
por: Zhao, Yicheng, et al.
Publicado: (2016)

Prevalence of classical swine fever in Karnataka, India
por: Choori, Prakash, et al.
Publicado: (2015)

The control of classical swine fever in wild boar
por: Moennig, Volker
Publicado: (2015)

Reemergence of Classical Swine Fever, Japan, 2018
por: Postel, Alexander, et al.
Publicado: (2019)

Classical Swine Fever in China-An Update Minireview
por: Zhou, Bin
Publicado: (2019)

Anti-Classical Swine Fever Virus Strategies
por: Fan, Jindai, et al.
Publicado: (2021)

Antigenic Characterization of Recombinant Hemagglutinin Proteins Derived from Different Avian Influenza Virus Subtypes
por: Mueller, Matthias, et al.
Publicado: (2010)

Classical Swine Fever Virus N(pro) Antagonizes IRF3 To Prevent Interferon-Independent TLR3- and RIG-I-Mediated Apoptosis
por: Hardy, Samuel, et al.
Publicado: (2021)

Classical Swine Fever Virus vs. Classical Swine Fever Virus: The Superinfection Exclusion Phenomenon in Experimentally Infected Wild Boar
por: Muñoz-González, Sara, et al.
Publicado: (2016)

African swine fever virus infection in Classical swine fever subclinically infected wild boars
por: Cabezón, Oscar, et al.
Publicado: (2017)

Highly pathogenic avian influenza virus H5N1 controls type I IFN induction in chicken macrophage HD-11 cells: a polygenic trait that involves NS1 and the polymerase complex
por: Liniger, Matthias, et al.
Publicado: (2012)

Complex Virus–Host Interactions Involved in the Regulation of Classical Swine Fever Virus Replication: A Minireview
por: Li, Su, et al.
Publicado: (2017)

MiR-140 inhibits classical swine fever virus replication by targeting Rab25 in swine umbilical vein endothelial cells
por: Xu, Panpan, et al.
Publicado: (2020)

Mitogen-Activated Protein Kinase Kinase 2, a Novel E2-Interacting Protein, Promotes the Growth of Classical Swine Fever Virus via Attenuation of the JAK-STAT Signaling Pathway
por: Wang, Jinghan, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_4nbchn5acmohehtfb2f6np7e7b