Variants in COMT, CYP3A5, CYP2B6, and ABCG2 Alter Quetiapine Pharmacokinetics

Quetiapine is an atypical antipsychotic widely used for the treatment of schizophrenia and the depressive episodes of bipolar disorder. The aim of this work was to investigate the effect of variants in relevant pharmacogenes in the pharmacokinetics of quetiapine and to exploratorily evaluate adverse...

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Detalles Bibliográficos
Autores principales: Zubiaur, Pablo, Fernández-Campos, Paula, Navares-Gómez, Marcos, Soria-Chacartegui, Paula, Villapalos-García, Gonzalo, Román, Manuel, Mejía-Abril, Gina, Ochoa, Dolores, Abad-Santos, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8540141/
https://www.ncbi.nlm.nih.gov/pubmed/34683865
http://dx.doi.org/10.3390/pharmaceutics13101573

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8540141/
https://www.ncbi.nlm.nih.gov/pubmed/34683865
http://dx.doi.org/10.3390/pharmaceutics13101573

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