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Performance of the plasma Aβ42/Aβ40 ratio, measured with a novel HPLC-MS/MS method, as a biomarker of amyloid PET status in a DPUK-KOREAN cohort

BACKGROUND: We assessed the feasibility of plasma Aβ42/Aβ40 determined using a novel liquid chromatography-mass spectrometry method (LC-MS) as a useful biomarker of PET status in a Korean cohort from the DPUK Study. METHODS: A total of 580 participants belonging to six groups, Alzheimer’s disease de...

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Detalles Bibliográficos
Autores principales: Jang, Hyemin, Kim, Ji Sun, Lee, Hye Joo, Kim, Chi-Hun, Na, Duk L., Kim, Hee Jin, Allué, José Antonio, Sarasa, Leticia, Castillo, Sergio, Pesini, Pedro, Gallacher, John, Seo, Sang Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8540152/
https://www.ncbi.nlm.nih.gov/pubmed/34686209
http://dx.doi.org/10.1186/s13195-021-00911-7