Mechanochemical Synthesis and Physicochemical Characterization of Previously Unreported Praziquantel Solvates with 2-Pyrrolidone and Acetic Acid

Two new solvates of the widely used anthelminthic Praziquantel (PZQ) were obtained through mechanochemical screening with different liquid additives. Specifically, 2-pyrrolidone and acetic acid gave solvates with 1:1 stoichiometry (PZQ-AA and PZQ-2P, respectively). A wide-ranging characterization of...

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Detalles Bibliográficos
Autores principales: Zanolla, Debora, Gigli, Lara, Hasa, Dritan, Chierotti, Michele R., Arhangelskis, Mihails, Demitri, Nicola, Jones, William, Voinovich, Dario, Perissutti, Beatrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8540171/
https://www.ncbi.nlm.nih.gov/pubmed/34683899
http://dx.doi.org/10.3390/pharmaceutics13101606

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8540171/
https://www.ncbi.nlm.nih.gov/pubmed/34683899
http://dx.doi.org/10.3390/pharmaceutics13101606

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