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Mechanochemical Synthesis and Physicochemical Characterization of Previously Unreported Praziquantel Solvates with 2-Pyrrolidone and Acetic Acid

Two new solvates of the widely used anthelminthic Praziquantel (PZQ) were obtained through mechanochemical screening with different liquid additives. Specifically, 2-pyrrolidone and acetic acid gave solvates with 1:1 stoichiometry (PZQ-AA and PZQ-2P, respectively). A wide-ranging characterization of...

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Detalles Bibliográficos
Autores principales:	Zanolla, Debora, Gigli, Lara, Hasa, Dritan, Chierotti, Michele R., Arhangelskis, Mihails, Demitri, Nicola, Jones, William, Voinovich, Dario, Perissutti, Beatrice
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8540171/ https://www.ncbi.nlm.nih.gov/pubmed/34683899 http://dx.doi.org/10.3390/pharmaceutics13101606

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