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Inhibition of 11β-HSD1 Ameliorates Cognition and Molecular Detrimental Changes after Chronic Mild Stress in SAMP8 Mice

Impaired glucocorticoid (GC) signaling is a significant factor in aging, stress, and neurodegenerative diseases such as Alzheimer’s disease. Therefore, the study of GC-mediated stress responses to chronic moderately stressful situations, which occur in daily life, is of huge interest for the design...

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Detalles Bibliográficos
Autores principales: Puigoriol-Illamola, Dolors, Companys-Alemany, Júlia, McGuire, Kris, Homer, Natalie Z. M., Leiva, Rosana, Vázquez, Santiago, Mole, Damian J., Griñán-Ferré, Christian, Pallàs, Mercè
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8540242/
https://www.ncbi.nlm.nih.gov/pubmed/34681264
http://dx.doi.org/10.3390/ph14101040