Cargando…
Inhibition of 11β-HSD1 Ameliorates Cognition and Molecular Detrimental Changes after Chronic Mild Stress in SAMP8 Mice
Impaired glucocorticoid (GC) signaling is a significant factor in aging, stress, and neurodegenerative diseases such as Alzheimer’s disease. Therefore, the study of GC-mediated stress responses to chronic moderately stressful situations, which occur in daily life, is of huge interest for the design...
Autores principales: | Puigoriol-Illamola, Dolors, Companys-Alemany, Júlia, McGuire, Kris, Homer, Natalie Z. M., Leiva, Rosana, Vázquez, Santiago, Mole, Damian J., Griñán-Ferré, Christian, Pallàs, Mercè |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8540242/ https://www.ncbi.nlm.nih.gov/pubmed/34681264 http://dx.doi.org/10.3390/ph14101040 |
Ejemplares similares
-
Understanding Epigenetics in the Neurodegeneration of Alzheimer’s Disease: SAMP8 Mouse Model
por: Griñán-Ferré, Christian, et al.
Publicado: (2018) -
Environmental Enrichment Modified Epigenetic Mechanisms in SAMP8 Mouse Hippocampus by Reducing Oxidative Stress and Inflammaging and Achieving Neuroprotection
por: Griñan-Ferré, Christian, et al.
Publicado: (2016) -
Chronic Mild Stress Modified Epigenetic Mechanisms Leading to Accelerated Senescence and Impaired Cognitive Performance in Mice
por: Puigoriol-Illamola, Dolors, et al.
Publicado: (2020) -
Epigenetic mechanisms underlying cognitive impairment and Alzheimer disease hallmarks in 5XFAD mice
por: Griñán-Ferré, Christian, et al.
Publicado: (2016) -
Environmental Enrichment Improves Cognitive Deficits, AD Hallmarks and Epigenetic Alterations Presented in 5xFAD Mouse Model
por: Griñán-Ferré, Christian, et al.
Publicado: (2018)