Activity of New Synthetic (2-Chloroethylthio)-1,4-naphthoquinones in Prostate Cancer Cells

Development of resistance to currently available standard therapies in advanced prostate cancer (PCa) emphasizes the need for novel therapeutic options. Here, we report the synthesis of new hybrid molecules consisting of 2-chloroethylthio and 1,4-naphthoquinone pharmacophores and describe their acti...

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Detalles Bibliográficos
Autores principales: Dyshlovoy, Sergey A., Pelageev, Dmitry N., Jakob, Lea S., Borisova, Ksenia L., Hauschild, Jessica, Busenbender, Tobias, Kaune, Moritz, Khmelevskaya, Ekaterina A., Graefen, Markus, Bokemeyer, Carsten, Anufriev, Victor Ph., von Amsberg, Gunhild
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8540265/
https://www.ncbi.nlm.nih.gov/pubmed/34681173
http://dx.doi.org/10.3390/ph14100949

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8540265/
https://www.ncbi.nlm.nih.gov/pubmed/34681173
http://dx.doi.org/10.3390/ph14100949

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