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Activity of New Synthetic (2-Chloroethylthio)-1,4-naphthoquinones in Prostate Cancer Cells
Development of resistance to currently available standard therapies in advanced prostate cancer (PCa) emphasizes the need for novel therapeutic options. Here, we report the synthesis of new hybrid molecules consisting of 2-chloroethylthio and 1,4-naphthoquinone pharmacophores and describe their acti...
Autores principales: | Dyshlovoy, Sergey A., Pelageev, Dmitry N., Jakob, Lea S., Borisova, Ksenia L., Hauschild, Jessica, Busenbender, Tobias, Kaune, Moritz, Khmelevskaya, Ekaterina A., Graefen, Markus, Bokemeyer, Carsten, Anufriev, Victor Ph., von Amsberg, Gunhild |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8540265/ https://www.ncbi.nlm.nih.gov/pubmed/34681173 http://dx.doi.org/10.3390/ph14100949 |
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