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Amorphous Solid Dispersions (ASDs): The Influence of Material Properties, Manufacturing Processes and Analytical Technologies in Drug Product Development

Poorly water-soluble drugs pose a significant challenge to developability due to poor oral absorption leading to poor bioavailability. Several approaches exist that improve the oral absorption of such compounds by enhancing the aqueous solubility and/or dissolution rate of the drug. These include ch...

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Detalles Bibliográficos
Autores principales: Iyer, Raman, Petrovska Jovanovska, Vesna, Berginc, Katja, Jaklič, Miha, Fabiani, Flavio, Harlacher, Cornelius, Huzjak, Tilen, Sanchez-Felix, Manuel Vicente
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8540358/
https://www.ncbi.nlm.nih.gov/pubmed/34683975
http://dx.doi.org/10.3390/pharmaceutics13101682