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Knockout of Hepatocyte Growth Factor by CRISPR/Cas9 System Induces Apoptosis in Hepatocellular Carcinoma Cells

Background: CRISPR/Cas9 system is a prokaryotic adaptive immune response system that uses noncoding RNAs to guide the Cas9 nuclease to induce site-specific DNA cleavage. Hepatocyte growth factor (HGF) is a well-known growth factor that plays a crucial role in cell growth and organ development. Accor...

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Detalles Bibliográficos
Autores principales: Lee, Han Ki, Lim, Heui Min, Park, See-Hyoung, Nam, Myeong Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8540514/
https://www.ncbi.nlm.nih.gov/pubmed/34683124
http://dx.doi.org/10.3390/jpm11100983