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Synthesis, Computational Analysis, and Antiproliferative Activity of Novel Benzimidazole Acrylonitriles as Tubulin Polymerization Inhibitors: Part 2

We used classical linear and microwave-assisted synthesis methods to prepare novel N-substituted, benzimidazole-derived acrylonitriles with antiproliferative activity against several cancer cells in vitro. The most potent systems showed pronounced activity against all tested hematological cancer cel...

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Detalles Bibliográficos
Autores principales: Beč, Anja, Hok, Lucija, Persoons, Leentje, Vanstreels, Els, Daelemans, Dirk, Vianello, Robert, Hranjec, Marijana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8540608/
https://www.ncbi.nlm.nih.gov/pubmed/34681276
http://dx.doi.org/10.3390/ph14101052