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HIF-Overexpression and Pro-Inflammatory Priming in Human Mesenchymal Stromal Cells Improves the Healing Properties of Extracellular Vesicles in Experimental Crohn’s Disease

Extracellular vesicles (EVs) derived from mesenchymal stromal cells (MSCs) have therapeutic potential in the treatment of several immune disorders, including ulcerative colitis, owing to their regenerative and immunosuppressive properties. We recently showed that MSCs engineered to overexpress hypox...

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Detalles Bibliográficos
Autores principales: Gómez-Ferrer, Marta, Amaro-Prellezo, Elena, Dorronsoro, Akaitz, Sánchez-Sánchez, Rafael, Vicente, Ángeles, Cosín-Roger, Jesús, Barrachina, María Dolores, Baquero, María Carmen, Valencia, Jaris, Sepúlveda, Pilar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8540690/
https://www.ncbi.nlm.nih.gov/pubmed/34681929
http://dx.doi.org/10.3390/ijms222011269