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Investigating Pathogenetic Mechanisms of Alzheimer’s Disease by Systems Biology Approaches for Drug Discovery

Alzheimer’s disease (AD) is the most common cause of dementia, characterized by progressive cognitive decline and neurodegenerative disorder. Abnormal aggregations of intracellular neurofibrillary tangles (NFTs) and unusual accumulations of extracellular amyloid-β (Aβ) peptides are two important pat...

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Detalles Bibliográficos
Autores principales: Yeh, Shan-Ju, Chung, Ming-Hsun, Chen, Bor-Sen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8540696/
https://www.ncbi.nlm.nih.gov/pubmed/34681938
http://dx.doi.org/10.3390/ijms222011280