Cargando…

Investigating Pathogenetic Mechanisms of Alzheimer’s Disease by Systems Biology Approaches for Drug Discovery

Alzheimer’s disease (AD) is the most common cause of dementia, characterized by progressive cognitive decline and neurodegenerative disorder. Abnormal aggregations of intracellular neurofibrillary tangles (NFTs) and unusual accumulations of extracellular amyloid-β (Aβ) peptides are two important pat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yeh, Shan-Ju, Chung, Ming-Hsun, Chen, Bor-Sen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8540696/ https://www.ncbi.nlm.nih.gov/pubmed/34681938 http://dx.doi.org/10.3390/ijms222011280

Ejemplares similares

Investigating the Role of Obesity in Prostate Cancer and Identifying Biomarkers for Drug Discovery: Systems Biology and Deep Learning Approaches
por: Yeh, Shan-Ju, et al.
Publicado: (2022)

Investigation of the Genome-Wide Genetic and Epigenetic Networks for Drug Discovery Based on Systems Biology Approaches in Colorectal Cancer
por: Yeh, Shan-Ju, et al.
Publicado: (2020)

Investigating Common Pathogenic Mechanisms between Homo sapiens and Different Strains of Candida albicans for Drug Design: Systems Biology Approach via Two-Sided NGS Data Identification
por: Yeh, Shan-Ju, et al.
Publicado: (2019)

Systems Biology Approaches to Investigate Genetic and Epigenetic Molecular Progression Mechanisms for Identifying Gene Expression Signatures in Papillary Thyroid Cancer
por: Yeh, Shan-Ju, et al.
Publicado: (2019)

Systems Drug Discovery for Diffuse Large B Cell Lymphoma Based on Pathogenic Molecular Mechanism via Big Data Mining and Deep Learning Method
por: Yeh, Shan-Ju, et al.
Publicado: (2022)

Multiple-Molecule Drug Design Based on Systems Biology Approaches and Deep Neural Network to Mitigate Human Skin Aging
por: Yeh, Shan-Ju, et al.
Publicado: (2021)

Remak's Diagnostic and Pathogenetic Investigations
Publicado: (1847)

Identifying Drug Targets of Oral Squamous Cell Carcinoma through a Systems Biology Method and Genome-Wide Microarray Data for Drug Discovery by Deep Learning and Drug Design Specifications
por: Lin, Yi-Chung, et al.
Publicado: (2022)

Investigating Core Signaling Pathways of Hepatitis B Virus Pathogenesis for Biomarkers Identification and Drug Discovery via Systems Biology and Deep Learning Method
por: Chang, Shen, et al.
Publicado: (2020)

Systems Approach to Pathogenic Mechanism of Type 2 Diabetes and Drug Discovery Design Based on Deep Learning and Drug Design Specifications
por: Chang, Shen, et al.
Publicado: (2020)

Computational Analysis of Pathogenetic Pathways in Alzheimer’s Disease and Prediction of Potential Therapeutic Drugs
por: Petralia, Maria Cristina, et al.
Publicado: (2022)

Ameloblastoma: A Review of Recent Molecular Pathogenetic Discoveries
por: Brown, Noah A., et al.
Publicado: (2015)

Bioinformatics and Systems Biology Approach to Identify the Pathogenetic Link Between Psoriasis and Cardiovascular Disease
por: Shi, Liping, et al.
Publicado: (2023)

Systems biology: An emerging strategy for discovering novel pathogenetic mechanisms that promote cardiovascular disease
por: Maron, Bradley A., et al.
Publicado: (2016)

A potential pathogenetic role of iron in Alzheimer's disease
por: Silvestri, Laura, et al.
Publicado: (2008)

Drug-Induced Photosensitivity: Clinical Types of Phototoxicity and Photoallergy and Pathogenetic Mechanisms
por: Di Bartolomeo, Luca, et al.
Publicado: (2022)

PATHOGENETIC MECHANISMS IN EXPERIMENTAL IMMUNE FEVER
por: Root, Richard K., et al.
Publicado: (1968)

Pathogenetic mechanisms of heatstroke and novel therapies
por: Bouchama, Abderrezak
Publicado: (2012)

Pathogenetic Mechanism of Procalcitonin in COVID-19
por: Wiedermann, Franz J
Publicado: (2021)

Melanosis of the Bladder: Possible Pathogenetic Mechanisms
por: Dupey, Justin E., et al.
Publicado: (2022)

Discovering common pathogenetic processes between COVID-19 and sepsis by bioinformatics and system biology approach
por: Lu, Lu, et al.
Publicado: (2022)

The GH-IGF-SST system in hepatocellular carcinoma: biological and molecular pathogenetic mechanisms and therapeutic targets
por: Pivonello, Claudia, et al.
Publicado: (2014)

Integrating ‘Omics’ Approaches to Prioritize New Pathogenetic Mechanisms for Mental Disorders
por: Cattaneo, Annamaria, et al.
Publicado: (2018)

Unravelling the Pathogenetic Mechanisms in Congenital Aortopathies: Need for an Integrative Translational Approach
por: Girdauskas, Evaldas, et al.
Publicado: (2020)

Systems Medicine Design for Triple-Negative Breast Cancer and Non-Triple-Negative Breast Cancer Based on Systems Identification and Carcinogenic Mechanisms
por: Yeh, Shan-Ju, et al.
Publicado: (2021)

Anxiety and depression in Alzheimer’s disease: a systematic review of pathogenetic mechanisms and relation to cognitive decline
por: Botto, Rossana, et al.
Publicado: (2022)

5-Fluorouracil-related encephalopathy: at least two distinct pathogenetic mechanisms exist - reply
por: Yeh, Kun-Huei, et al.
Publicado: (1998)

The Pathogenetic Picture
por: Fincke, B.
Publicado: (1891)

Pathogenetic Mechanisms of T Cell Dysfunction in Chronic HBV Infection and Related Therapeutic Approaches
por: Fisicaro, Paola, et al.
Publicado: (2020)

Catecholamine cardiomyopathy: review and analysis of pathogenetic mechanisms.
por: Jiang, J. P., et al.
Publicado: (1990)

Pathogenetic mechanism of oral granulomatous diseases: An update
por: Abdul, Nishath Sayed
Publicado: (2020)

Pathogenetic mechanisms of severe acute respiratory syndrome
por: Guo, Yong, et al.
Publicado: (2008)

Helicobacter pylori and Gastric Cancer: Pathogenetic Mechanisms
por: Salvatori, Silvia, et al.
Publicado: (2023)

Drug Target Identification and Drug Repurposing in Psoriasis through Systems Biology Approach, DNN-Based DTI Model and Genome-Wide Microarray Data
por: Zhan, Yu-Ping, et al.
Publicado: (2023)

Differences in the pathogenetic characteristics of prostate cancer in the transitional and peripheral zones and the possible molecular biological mechanisms
por: Yu, Xudong, et al.
Publicado: (2023)

Bioinformatics and systems biology approach to identify the pathogenetic link of Long COVID and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
por: Lv, Yongbiao, et al.
Publicado: (2022)

Latest Evidence Regarding the Effects of Photosensitive Drugs on the Skin: Pathogenetic Mechanisms and Clinical Manifestations
por: Lozzi, Flavia, et al.
Publicado: (2020)

Robust Design of Biological Circuits: Evolutionary Systems Biology Approach
por: Chen, Bor-Sen, et al.
Publicado: (2011)

Systems biology approaches for advancing the discovery of effective drug combinations
por: Ryall, Karen A, et al.
Publicado: (2015)

Insulin Resistance and Cancer Risk: An Overview of the Pathogenetic Mechanisms
por: Arcidiacono, Biagio, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_ele3t0418dh9fqbd6rum1ngkj2