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New N-Substituted-1,2,4-triazole Derivatives of Pyrrolo[3,4-d]pyridazinone with Significant Anti-Inflammatory Activity—Design, Synthesis and Complementary In Vitro, Computational and Spectroscopic Studies

Regarding that the chronic use of commonly available non-steroidal and anti-inflammatory drugs (NSAIDs) is often restricted by their adverse effects, there is still a current need to search for and develop new, safe and effective anti-inflammatory agents. As a continuation of our previous work, we d...

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Detalles Bibliográficos
Autores principales: Szczukowski, Łukasz, Krzyżak, Edward, Wiatrak, Benita, Jawień, Paulina, Marciniak, Aleksandra, Kotynia, Aleksandra, Świątek, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8540742/
https://www.ncbi.nlm.nih.gov/pubmed/34681894
http://dx.doi.org/10.3390/ijms222011235