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New N-Substituted-1,2,4-triazole Derivatives of Pyrrolo[3,4-d]pyridazinone with Significant Anti-Inflammatory Activity—Design, Synthesis and Complementary In Vitro, Computational and Spectroscopic Studies
Regarding that the chronic use of commonly available non-steroidal and anti-inflammatory drugs (NSAIDs) is often restricted by their adverse effects, there is still a current need to search for and develop new, safe and effective anti-inflammatory agents. As a continuation of our previous work, we d...
Autores principales: | Szczukowski, Łukasz, Krzyżak, Edward, Wiatrak, Benita, Jawień, Paulina, Marciniak, Aleksandra, Kotynia, Aleksandra, Świątek, Piotr |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8540742/ https://www.ncbi.nlm.nih.gov/pubmed/34681894 http://dx.doi.org/10.3390/ijms222011235 |
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