Cargando…

Targeting the Pentose Phosphate Pathway for SARS-CoV-2 Therapy

SARS-CoV-2 is causing the coronavirus disease 2019 (COVID-19) pandemic, for which effective pharmacological therapies are needed. SARS-CoV-2 induces a shift of the host cell metabolism towards glycolysis, and the glycolysis inhibitor 2-deoxy-d-glucose (2DG), which interferes with SARS-CoV-2 infectio...

Descripción completa

Detalles Bibliográficos
Autores principales: Bojkova, Denisa, Costa, Rui, Reus, Philipp, Bechtel, Marco, Jaboreck, Mark-Christian, Olmer, Ruth, Martin, Ulrich, Ciesek, Sandra, Michaelis, Martin, Cinatl, Jindrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8540749/
https://www.ncbi.nlm.nih.gov/pubmed/34677415
http://dx.doi.org/10.3390/metabo11100699