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Acacetin Inhibits the Growth of STAT3-Activated DU145 Prostate Cancer Cells by Directly Binding to Signal Transducer and Activator of Transcription 3 (STAT3)

Signal transducer and activator of transcription 3 (STAT3) plays a critical role in the formation and growth of human cancer. Therefore, STAT3 is a therapeutic target for cancer drug discovery. Acacetin, a flavone present in various plants, inhibits constitutive and inducible STAT3 activation in STA...

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Detalles Bibliográficos
Autores principales: Yun, Sun, Lee, Yu-Jin, Choi, Jiyeon, Kim, Nam Doo, Han, Dong Cho, Kwon, Byoung-Mog
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8540902/
https://www.ncbi.nlm.nih.gov/pubmed/34684783
http://dx.doi.org/10.3390/molecules26206204