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Linagliptin Protects against Endotoxin-Induced Acute Kidney Injury in Rats by Decreasing Inflammatory Cytokines and Reactive Oxygen Species

Septic shock can increase pro-inflammatory cytokines, reactive oxygen species (ROS), and multiple organ dysfunction syndrome (MODs) and even lead to death. Dipeptidyl peptidase-4 (DPP-4) inhibitors have been proven to exert potential antioxidant and anti-inflammatory effects. We investigated the eff...

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Detalles Bibliográficos
Autores principales: Wu, Tsung-Jui, Hsieh, Yi-Jen, Lu, Chia-Wen, Lee, Chung-Jen, Hsu, Bang-Gee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8540923/
https://www.ncbi.nlm.nih.gov/pubmed/34681847
http://dx.doi.org/10.3390/ijms222011190