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The Novel Application of Geometric Morphometrics with Principal Component Analysis to Existing G Protein-Coupled Receptor (GPCR) Structures

The G protein-coupled receptor (GPCR) superfamily is a large group of membrane proteins which, because of their vast involvement in cell signalling pathways, are implicated in a plethora of disease states and are therefore considered to be key drug targets. Despite advances in techniques to study th...

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Detalles Bibliográficos
Autores principales: Wiseman, Daniel N., Samra, Nikita, Román Lara, María Monserrat, Penrice, Samantha C., Goddard, Alan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8541025/
https://www.ncbi.nlm.nih.gov/pubmed/34681177
http://dx.doi.org/10.3390/ph14100953