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The Novel Application of Geometric Morphometrics with Principal Component Analysis to Existing G Protein-Coupled Receptor (GPCR) Structures
The G protein-coupled receptor (GPCR) superfamily is a large group of membrane proteins which, because of their vast involvement in cell signalling pathways, are implicated in a plethora of disease states and are therefore considered to be key drug targets. Despite advances in techniques to study th...
Autores principales: | Wiseman, Daniel N., Samra, Nikita, Román Lara, María Monserrat, Penrice, Samantha C., Goddard, Alan D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8541025/ https://www.ncbi.nlm.nih.gov/pubmed/34681177 http://dx.doi.org/10.3390/ph14100953 |
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